For further information, please email the study team at

Principal Investigator: Associate Professor Kelly Jones. Email:; Phone: 021 246 0587.

Study manager: Dr. Devaki de Silva. Email:; Phone: 021 837 175


Fatigue is a common and persistent deficit in up to 92% of stroke survivors that can negatively impact functioning. It is imperative that new strategies be developed to tackle post-stroke fatigue, a debilitating but often overlooked sequelae of stroke. Cognitive and behavioural (educational) interventions for fatigue have been successful in other conditions (e.g. traumatic brain injury, multiple sclerosis, chronic fatigue syndrome), but have not been fully examined in the context of stroke. Building on promising findings from our pilot study, this full-scale randomised controlled trial aims to assess the effect of the intervention on reducing physical, psychological and mental fatigue and improving quality of life in stroke survivors. Family carer quality of life and burden, as well as impact of the intervention on other functional outcomes and costs will also be examined. This trial has potential to improve quality of life and day-to-day functioning for stroke survivors and their families.

Design: Randomised Controlled Trial

Study population:

There are opportunities for 200 adults (aged 18 years or older) with clinically significant fatigue at 3 to 18-months after first-ever stroke to take part. A nominated person who helps to take care of the person with stroke can also participate, if available. People with all types of stroke will be included.


Fatigue is defined as “feeling constantly weary, tired and lacking energy or strength. These feelings and symptoms are present even after a rest or sleep”.

Inclusion criteria:

  1. Clinically significant fatigue at 3 to 18-months after first-ever stroke;
  2. Living in the study areas (Auckland, Waikato);
  3. Ability to converse in English;
  4. Able to provide informed consent.


  • Kelly Jones
  • Valery Feigin
  • Rita Krishnamurthi
  • Suzanne Barker-Collo
  • Irene Zeng
  • Braden Te Ao

Timeline: 01 October 2018 to 30 September 2022

Recruitment start date: 01 March 2019

Funded by: Health Research Council of New Zealand

Budget: $1.18million