Primary Prevention of Stroke in the Community (PRESCO)


  • Dr Rita Krishnamurthi -

Stroke is a major cause of death and disability worldwide, yet 90% of strokes can be prevented by adequate control of modifiable risk factors (e.g. high blood pressure, diabetes, smoking) through lifestyle modifications and medications. Individuals at a high risk of stroke can be identified by their family doctor through a cardiovascular disease risk calculator (PREDICT).

Those at a high 5-year risk should be prescribed medications and/or given recommendations to lifestyle changes to reduce cardiovascular risk. However, adherence to these recommendations is low, resulting in preventable strokes. Health/Wellness Coaching is a psychological intervention that may enhance adherence to doctor’s recommendations, and reduce stroke risk.

This study aims to determine the feasibility of a planned randomised clinical trial to test the effectiveness of health/wellness coaching for the primary prevention of stroke and cardiovascular disease in the community.


The aim of the study is to help identify any issues that need to be addressed before commencing a full scale randomised clinical trial to test the effectiveness of Health and Wellness Coaching (HWC) in reducing the risk of stroke and cardiovascular disease in the community.


This study is a phase II, open label, single centre randomised control trial (n=24) addressing feasibility issues of HWC coaching for primary stroke prevention in high stroke and CVD risk subjects to inform the design and methodology of statistically powered phase III randomised controlled trial.

Outcome Measures

The main outcome of the study will be feasibility of screening for eligible participants at primary healthcare practices in Auckland, rate of recruitment, rate of retention in the study and level of completion of case record forms and feedback from study participants. Relevant information to be collected in the full trial such as demographic information and other relevant medical information will be recorded for each study participant. To assess behaviour modification, each study participant will complete questions on general health and lifestyle information such as smoking status, diet, exercise, and medications during the phone interview at baseline and 3 months after the randomisation.